姓名:卿国良
单位:350vip葡亰集团医学研究院
职称:院长助理、教授、博导
邮箱:qingguoliang@whu.edu.cn
联系电话:027-68750015
研究方向:
1.肿瘤细胞-微环境炎性细胞代谢调控环路
2.肿瘤的靶向治疗
代表性论著:
1.Yue M, Jiang J, Gao P, Liu H, and Qing G*. Oncogenic Myc activates a feedforward circuit promoting essential amino acid metabolism and tumorigenesis. Cell Reports, 2017 In Press.
2.Wang Z, Hu Y, Xiao D, Liu C, Xu Y, Shi X, Jiang P, Huang L, Li P, Liu H, and Qing G*. Stabilization of Notch1 by the Hsp90 Chaperone is Crucial for T-Cell Leukemogenesis. Clinical Cancer Research, 23: 3834-3846, 2017.
3.Xiao D, Yue M, Su H, Ren P, Jiang J, Li F, Hu Y, Du H, Liu H, and Qing G*. Polo-like Kinase-1 Regulates Myc Stabilization and Activates a Feed-Forward Circuit Promoting Tumor Cell Survival. Molecular Cell, 64: 493-506, 2016.
4.Gan L, Xiu R, Ren P, Yue M, Su H, Guo G, Xiao D, Yu J, Jiang H, Liu H, Hu G and Qing G*. Metabolic targeting of oncogene MYC by selective activation of the proton-coupled monocarboxylate family of transporters. Oncogene, 35: 3037-48, 2016.
5.Qing G, Li B, Liu X, Skuli N, Mayes P, Wide DR, Maris JM, Thompson CB, and Simon MC. ATF4 regulates MYC-mediated cell death upon glutamine deprivation. Cancer Cell, 22:631-644, 2012.